Yes, it is very expensive and for folks on Medicare, at least until next year, a problem BUT...it is really important that people get through their treatments without breaks as much as possible, and without getting into a really debilitated state -- so compared to other things most of us might spend money on, it is cheap! (And we are both retired, Barry on Medicare, I have state pharmacy insurance but it doesn't cover him -- so we completely relate to the issue). Dealing with Cisplatin, one of the very worse offenders, I think that the need for the best anti-nausea drug should have been anticipated. Can't imagine anyone doing it on Compazine, maybe some have but...

Interestingly, the serotonin drugs apparently do not work well for situations like seasickness, whereas compazine does.

Zofran is about 1/3 to 1/2 the price in Canada -- btw.

Gail