Thanks everyone. Had first Erbitux infusion last Tuesday and rash for about 2 days that has since disappeared. Also a headache and achy for about 24 hours. A little scary in that he had a reaction to the infusion at first and had to get benadryl and solumedrol and they slowed the rate down temporarily. I was extremely impressed with the staff's response and knowledge and want to emphasize what others have stated on this board- go to an NCI CCC for treatment. Experience and a mulit-disciplinary team approach counts and I have seen that first hand. Start radiation tomorrow- how long before those effects start? I know everyone is different but from what I have read and heard it builds over time and the first week is not too bad typically?