Hellion, I'm really sorry that you are in the same boat as we are. Maybe you would like to ask your doctor what kind of outcomes he has got for each option so far. Even for John's phase 1 trial, the doctor was able to tell us how many patients with head and neck cancers have seen the tumours shrinking and how many have had tumour reduction. That may help in making a decision.

Gloria
She stood in the storm, and when the wind did not blow her way, she adjusted her sails... Elizabeth Edwards

Wife to John,dx 10/2012, BOT, HPV+, T3N2MO, RAD 70 gy,Cisplatinx2 , PEG in Dec 6, 2012, dx dvt in both legs after second chemo session, Apr 03/13 NED, July 2013 met to lungs, Phase 1 immunotherapy trial Jan 18/14 to July/14. Taxol/carboplatin July/14. Esophagus re-opened Oct 14. PEG out April 8, 2015. Phase 2 trial of Selinexor April to July 2015. At peace Jan 15, 2016.