I like your idea. They do close weekends, some on holidays, and don't have a full answer why, but cancer repopulation, angiogenesis, hypoxia may factor in, and tumor cells are different than regular cells, and sure studies were done finding this was the most effective way for tumor kill, so far, in most cases, since regular cells have a certain cell cycle, and death, but cancer cells don't, and that factors in probably too.There are other ways to deliver radiation that can increase boost dosage, more fraction sizes, hyperfractioned radiation, which is more than once a day, accelerated fractions for shorter duration over the course of the treatment with same dosage, so that may factor in for any planned lapses, type of treatment. Certain organs, structure, like skin, can recover in less than a day, and each has a maximum dosage level before unacceptable toxicities begin, so that is factored in. In some SCCHN they use split dosages (hyerfractions) 2x a day treatments, and even 6 day fractions in 6 weeks (accelerated fractions) instead of standard 7 or adding on a day towards the end of treatment to increase total Gy. There is brachytherapy that uses one time high dose or several weeks, or longer implant doses. I had HD-IORT..high dose Intraoperative radiation therapy, in addition to IMRT. IORT is done during surgery directly to the exposed tumor, which gives a one shot high dose of radiation from 10-25 Gy, which would take two to four weeks with IMRT.. Radiostatic Radiosurgery uses high dose in less time also, like in 5 treatments. They are working on radiation to be more effective with medications, even with Chemo, administered during radiation to make tumors more radiosensitive, less hypoxic, and others.


10/09 T1N2bM0 Tonsil
11/09 Taxo Cisp 5-FU, 6 Months Hosp
01/11 35 IMRT 70Gy 7 Wks
06/11 30 HBO
08/11 RND PNI
06/12 SND PNI LVI
08/12 RND Pec Flap IORT 12 Gy
10/12 25 IMRT 50Gy 6 Wks Taxo Erbitux
10/13 SND
10/13 TBO/Angiograph
10/13 RND Carotid Remove IORT 10Gy PNI
12/13 25 Protons 50Gy 6 Wks Carbo
11/14 All Teeth Extract 30 HBO
03/15 Sequestromy Buccal Flap ORN
09/16 Mandibulectomy Fib Flap Sternotomy
04/17 Regraft hypergranulation Donor Site
06/17 Heart Attack Stent
02/19 Finally Cancer Free Took 10 yrs