I don't know the normal Zofran protocol with Cisplatin. But do ask tomorrow at your CCC's infusion center.

I took it the last week or so of Radiation treatments and it worked real well, but they had to use anti-nausea suppositories (no fun experience that I couldn't even imagine) to first get me under-control because I would just barf up the Zofran.

Mine was a liquid Zofran (Ondansetron Hydrochloride) 10ML's down the PEG tube three times a day.

You want to really stay on top of nausea because if you can't keep anything down it will led to dehydration in just a matter of a few days and then you have to get saline IV's. Dehydration is a real mess - weak, disorientation ... no fun, so save it for the end, or not at all, if you can.