There are quite a few of us here who aren't smokers or drinkers, and some quite young - for me it was chronic irritation to that area of my tongue. I would be very surprised if comes back HPV positive.. For this cancer, surgery, then rads and chemo is the best treatment. Be agressive from the start. Hugs and good luck.

Cheryl : Irritation - 2004 BX: 6/2008 : Inflam. BX: 12/10, DX: 12/10 : SCC - LS tongue well dif. T2N1M0. 2/11 hemigloss + recon. : PND - 40 nodes - 39 clear. 3/11 - 5/11 IMRT 33 + cis x2, PEG 3/28/11 - 5/19/11 3 head, 2 chest scans - clear(fingers crossed) HPV-, No smoke, drink, or drugs, Vegan