Lj, I should have mentioned in my post that a long time friend of mine has been on the 5fu pump off and on for many months now while battling liver cancer. He is able to go about his daily life with some constraints- he gets tired earlier in the day, reacts to cold or damp weather more, not much appetite, but still "going and doing". Hope there will be some folks here who have experience with it. Amy in the Ozarks