Karen,

P16 is a marker that is expressed when the proteins of HPV expression have been expressed. So it indicates a tumor that is likely a result of HPV infection. It is puzzling that the lab did not also detect HPV. But then again no test is perfect. It may be that on that day, with the laboratory test used, HPV was not detected but indeed was really there.

If it is important to him or you I would get retested or at a minimum have someone familiar with HPV explain this HPV neg/P16 pos.




David

Age 58 at Dx, HPV16+ SCC, Stage IV BOT+2 nodes, non smoker, casual drinker, exercise nut, Cisplatin x 3 & concurrent IMRT x 35,(70 Gy), no surgery, no Peg, Tx at Moffitt over Aug 06. Jun 07, back to riding my bike 100 miles a wk. Now doing 12 Spin classes and 60 outdoor miles per wk. Nov 13 completed Hilly Century ride for Cancer, 104 miles, 1st Place in my age group. Apr 2014 & 15, Spun for 9 straight hrs to raise $$ for YMCA's Livestrong Program. Certified Spin Instructor Jun 2014.