Patty. Take whatever you need to make yourself comfortable. The dr gave Jim a lot of meds and he was not real consistent in taking them. She said for him not to be afraid to take whatever has been prescribed. She made it very clear--if you are in pain, then get those meds in your body for relief. We started the patches at "25", now he is up to "125" and the oxycodone helps. Good luck and sorry to see you going through so much. Keep us posted...............Claudia