My husband has never had mean in his body either but with this disease the anxiety has a real hold on him which translates into, maybe not mean, but the worst case of PMS a man ever had! yee haw! The antidepressant and antianxiety meds for him have helped - the antianxiety med for me has controlled my own smart mouth This is not a pretty scenario for anyone but if you just keep putting one foot in front of the other it's doable. One day at a time....