Everyone is different. I had an unknown primary, most likely oropharynx, HPV+. My team felt that surgery first was the best bet. Their logic was, "If we remove 99% of the cancer, that's less treatment we'll have to do." I had a selective neck dissection and the tumors were extracapsulated so I had chemo/rads anyway but 30 rads and 6 weekly chemo infusions. based on the aggressiveness of my cancer, I'm glad they went in and got it.

Good luck, positive thoughts and prayers whatever is decided.

"T"