Gordon, my dad also had a recurrent/persistent tumor on his right neck and underwent TPF (Taxotere + Cisplatin + 5 FU) for 3 cycles but it did not shrink his tumor. He underwent surgery followed by re-radiation (he had 60gy, the first time). With another recurrence, he was on gefitinib and that did keep him kicking for another 6 months before cardiac arrest took him away due to multiple health issues.

If Caco is around, she can suggest her dad's treatment - clinical trial. Last that we heard was this: http://clinicaltrials.gov/show/NCT01458392

Thread: http://oralcancersupport.org/forums...mp;Words=caco&Search=true#Post158838