 Senior Member (100+ posts)
Joined: Feb 2005 Posts: 118 Likes: 1 | Caco,
I participated in a Phase 1 clinical trial of Alimta with TRC 102 from Tracon Pharmaceuticals NCT 0062159 from 3/2/09 until 4/10/10. A RUL nodule disappeared and a right hilar lymph node decreased in size from 2.4 cm to 1.4 cm and then maintained until my 3/10 PET which showed that the lymph node had increased to 2.2 cm. At that time I dropped from the trial. The phase 1 portion of the trial had actually stopped several months earlier, but, because I was continuing to benefit from the meds, Tracon continued to provide them at no charge with the trial protocol continuing. I had such minimal side effects that I was able to travel, camp, do volunteer activities throughout the year. I believe there was a presentation made at ASCO detailing the results of this phase 1, and I recall that I was one of the few who benefited for this period of time with this drug combo. I have not followed the further testing, if, in fact, there were additional phases.
Where is your dad in his treatment plan now?
Be well. Zenda
12/04 SCC Tonsil, Stage IV T3N2BM0. Mod RND, resect right oropharynx, free-flap, resect right tongue base. Erbitux,Docetaxel,RT X 33. 6/08 Mets lung, hilar lymph node:Carboplatin, Docetaxel. 2010 2nd clinical trial:lung clear, node stable. ORN,trismus,dysphagia. 8-10/2012 cryoablation,brachytherapy,cyberknife to lymph node. 12/12 NED. 6/13 Mets RLL lung: 8/13 cyberknife. 11/13 NED.
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