Gordon, I'm sorry to hear the tumor is not respnding. I had Taxotere, twice, and it can cause "hand and foot syndrome" you describe. To help reduce the toxicities, cryotherapy, like putting cold mitts on hands, feet, and for mucositus, chewing ice or drinking something cold may help ruin infusions. For nail changes, use several drops tree tee oil in a small amount of nail polish, apply to nails, cuticles on hands and feet daily, Sally absence hard as nails. For small cut put crazy glue

I heard of TPF bring usdd to reduce tumor size during treatment if growth is rapid. but that has Taxotere too, in addition to cisplatin and 5-FU. There are different combinations too with similar varients. I also heard of Erbitux being used for maintenance.

I don't recall where your recurrence is, but you mention the left neck. My doctor does intraopertive operative radiation treatment for head and neck cancer, which I did in August.

I hope this helps.