Hey,

I like Charm too. :-) And do VERY MUCH appreciate having a more balanced and more faceted opinions and experiences offered here. Having exposure to more options can only be helpful, if nothing more, educational. Ultimately, it is the patient and those trusted to make the critical analysis and decisions.

Of course, if you of all ppl,as well as PaulB, Christine and others who experienced recurrence had been offered more aggressive options and felt strongly of improved CR, and knew all the issues associated with recurrence would have at least given it serious consideration, if not, proceed that way.

As to any peer review published findings on HPV+ OC response vs non-HPV+ strains, there are none yet. There must be some trials but at this point any results would be classified as anecdotal. So the question becomes how much is one willing to gamble their live with something that is not stamped standard of care.

When I asked my surgeon about trials, his quip was they primarily are done to seek the balance of best outcomes with the least side effects. I like you, have a strong hunch that down the road definitive studies will find that HPV+ strains of OC can be treated with less but equally or even better outcomes.

However, until this is proven, I guess I am playing it safe and have rationalized the potential of increased short and long tern side effects more than offset all the issues related to recurrences.

That said, each person needs to make as informed decision for themselves and the more lively yet respectful opinions get posted the better.

Don


Don
Male, 57 - Great health except C
Dec '12
DX: BOT SCC T2N2bMx, Stage 4a, HPV+, multiple nodes
1 tooth out
Jan '13
2nd tooth out
Tumor Board -induction TPF (3 cycles), seq CRT
4-6/2013
CRT 70gr 2x35, weekly carbo150
ended 5/29,6/4
All the details, join at http://beatdown.cognacom.com