cclark, there is another HBO benefit not mentioned. This is an incredible improvement in vision. If he wears glasses, he will find he does not need them. In case he wonders, this is why he will be given an eye test a couple of times. After wearing reading glasses for years and years, I suddenly realized I was reading a paperback book unassisted. For most people, this fades back to pre-tx status in a few weeks. I, however am a lucky one who kept the change. I do not see any downside to HBO. Yes, it is a lot of time, but the benefits are many. I was one of the few H&N patients where I was treated; most were wounds that were not healing. Business is good. Where I went, they have just doubled their capacity.