Your husband is probably quite fatigued at this point in his treatment. His entire being might be focused on just staying well enough to go in for the daily radiation sessions. At this point, my husband lost all interest in things, even watching his favorite shows on the iPad in bed. He was also bothered by the thickened neck as a result of the collection of lymphatic fluid. He wasn't a vain man, but he didn't like what he saw in the mirror.

Have you mentioned the listlessness to the doctors? They may be able to prescribe some anti-anxiety mess for him. It may only be for a short time and can help with his mood.

Gloria
She stood in the storm, and when the wind did not blow her way, she adjusted her sails... Elizabeth Edwards

Wife to John,dx 10/2012, BOT, HPV+, T3N2MO, RAD 70 gy,Cisplatinx2 , PEG in Dec 6, 2012, dx dvt in both legs after second chemo session, Apr 03/13 NED, July 2013 met to lungs, Phase 1 immunotherapy trial Jan 18/14 to July/14. Taxol/carboplatin July/14. Esophagus re-opened Oct 14. PEG out April 8, 2015. Phase 2 trial of Selinexor April to July 2015. At peace Jan 15, 2016.