Seth, when the MO suggested taxol and carboplatin, she called them "the bread and butter stuff." John can only have 80% of the normal dose as his blood count is so low. The third chemo when it happens on October 14 will be further reduced. I know this will help him deal better with the side effects but I have no idea if remains effective against the cancer. He will have a scan on Oct 17 and I guess at that point we find out.

Once more unto the breach ...

Gloria
She stood in the storm, and when the wind did not blow her way, she adjusted her sails... Elizabeth Edwards

Wife to John,dx 10/2012, BOT, HPV+, T3N2MO, RAD 70 gy,Cisplatinx2 , PEG in Dec 6, 2012, dx dvt in both legs after second chemo session, Apr 03/13 NED, July 2013 met to lungs, Phase 1 immunotherapy trial Jan 18/14 to July/14. Taxol/carboplatin July/14. Esophagus re-opened Oct 14. PEG out April 8, 2015. Phase 2 trial of Selinexor April to July 2015. At peace Jan 15, 2016.