I tried to take pain and nausea meds on a time schedule and NOT by how I felt. If you wait til you are hurting to take a pain med IMO, you're too late. I think that's the difference between pain management and pain response. Same with the zofran. If you take it when you're queezy you'll be queezy til it kicks in.

The exception to the above was during recovery when I might see how long I could go without one or the other until neither were needed. Made a few mistakes there...