Jay-I am so sorry to hear of this development. It is similar to news my husband and I received at end of April, following 3 month followup PET scan and a biopsy. He has focused on putting one foot in front of the other, work-wise and children-wise, while I have done much research and become more active on this site seeking information--and finding not only info, but great compassion.
He has a very small malignancy in the hilar lymph node of lung. We are still evaluating treatment options, but 3 opinions thus far indicate that surgery is likely not an option for us, I believe because it is in the lymph node. The likely scenario is a radiation approach, with chemo as a sensitizer. (This is a new approach that is being tried at Hopkins for certain HPV cases.)
Is your wife's nodule in the actual lung or in the lymph node? Also, your tagline does not indicate HPV+. Best of luck with the PET Wednesday. Please keep us posted. I am happy for you that you have been presented with a plan of action.
Best to you both,
Mary

Mary
Caregiver to husband, 60
Dx Sept '12 SCC BOT T2N2aMo, Stage IV, HPV+
Oct '12 Sub.Gland transfer
Nov-Dec '12 IMRT x 33 + cisplatin x7
March '13 PET/CT: 2 spots on lungs; (BOT & neck lymphs NED)
April '13 Biopsy: 1 = malignant right hilar lymph (met from HNSCC)p16
9/13: 33 rounds IMRT to lungs; carboplatinx7
CT w/contrast 12/30/13: 2 spots left hilar lymph. biopsy confirms SCC
30 rounds IMRT to left lung; treatment ended 5/29/14
Sept 2014--CT clear; December 2014 CT clear