OP Patient Advocate (1000+ posts) Joined: Jan 2009 Posts: 1,844 | Don, I think your question is really too generalized to answer my friend as I can't, nor do I know anyone that would know the specific leucine content of every whey product on the market. Also consider that age, sex, activity levels, lean body mass percentages etc are all going to be a factor of how much protein/leucine is needed. Everyone is going to be different.
So I will give you information from both Drs Layne Norton and Donald Layman, PhDs that have been published in the Journal of Nutrition on the subject of leucine and protein intake.
"While the combination of high-frequency stimulation and growth factors increases protein synthesis postexercise, synthesis is not fully stimulated and skeletal muscle remains catabolic without supplemental dietary leucine, either alone or as a part of protein or an amino acid mixture. Supplemental leucine allows for the muscle to achieve maximum protein synthesis and anabolic recover"
"Carbohydrates, nonessential amino acids, and other essential amino acids do not have stimulatory effects on protein synthesis when compared with leucine. However, in most cases, the combination of amino acid supplements with carbohydrates produces additive effects on the stimulation of the PI3-kinase and mTOR pathways, producing the maximum rates of protein synthesis during recovery"
"The impact of supplemental amino acids and carbohydrates on muscle protein synthesis was further evaluated by Volpi et al. They reported age-related differences in how subjects responded to protein and carbohydrates. In both young adults (∼30 y.o.) and older adults (∼69 y.o.) supplemental essential amino acids produced an anabolic effect on muscle protein synthesis. Further, combination of the essential amino acids with carbohydrates produced an additive enhancement of muscle protein synthesis in the young adults. However, in older adults, addition of carbohydrates (producing increased plasma insulin) eliminated the anabolic effect of supplemental amino acids. These authors suggested that the presents of carbohydrates in nutritional supplements may impair the anabolic effect of muscle protein synthesis in older adults."
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