I don't think working out has anything to do with how you react to chemo, in that case, I should never had a problem. I ran, biked, swam, boxed, and lifted weights, since I was 15, amongst several martial arts programs in between, and all my jobs required me to be physicaly fit, and be a deterrent, sometimes physically. I started chemo at 245 lbs, and after a severe reaction to the same chemo, Taxotere, Cisplatin. 5-FU, near death, I was 130lbs in less than a month. The side effects are too numerous to list. I think of it similar to an allergic reaction, some have no problems to certain foods, and some do. Can't do much to change that, just change the food, limit amount of exposure, duration, in this case toxin, if you can, and sometimes all it takes is once, and that's why they give you all the other meds to lessen the toxicities and side effects.