Thanks for the info. I know of other ways for cell loss, cell death is by necrosis, apoposis, exfoliation and metasteses, so it is possible the immune system is involved in the process, but I don't know if that would satisfy me enough to rely on without treatment, afterwards probably. Would a biopsy still show trace of the dead cells, if the primary is found? The stats are out there, and have read them, that the left, I believe, palentine or lingual tonsil is the majority of cases for HPV-16 positive in H&N, next is BOT, altough both are often grouped together. Sometimes they even find that some oral cancers were originally misdiagnosed, and were really Oropharyngeal Cancer. Often both structures are involved, tonsil, BOT, as was in my case.