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#95831 05-21-2009 06:11 AM
Joined: Mar 2008
Posts: 3,082
Patient Advocate (old timer, 2000 posts)
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Patient Advocate (old timer, 2000 posts)

Joined: Mar 2008
Posts: 3,082
Just had my first infusion of Carboplatin yesterday and so far no noticeable effects except for a "funny" feeling on the scars of my neck and wrist from the surgery. Nothing was mentioned in the literature about this - anybody else who had Carboplatin have any ideas? Also how long before side effects kick in generally, I only have two more to go and so far this feels a lot better than the Erbitux which started chewing up my skin immediately,


65 yr Old Frack
Stage IV BOT T3N2M0 HPV 16+
2007:72GY IMRT(40) 8 ERBITUX No PEG
2008:CANCER BACK Salvage Surgery
25GY-CyberKnife(5) 3 Carboplatin
Apaghia /G button
2012: CANCER BACK -left tonsilar fossa
40GY-CyberKnife(5) 3 Carboplatin

Passed away 4-29-13
Joined: Jan 2009
Posts: 253
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Gold Member (200+ posts)

Joined: Jan 2009
Posts: 253
Charm:
I do Carboplatin weekly with my radiation. I've not noticed any side effects with it, however, I'm probably not the best person to respond as I did very well with chemo in general.

Sandy


Sandy 56, BOT SCC Biopsy 1/21/09 Stage 3, T3NXM0.
Finished 3 cycle induction chemotherapy 4/7/09. (Chisplatin, 5-fu and Texotere). Re-staged 4/20/09,(very successful.) Will start Carboplatin/radiation 2 Gy/5 days/7 weeks (Tomotherapy) starting May 4th. Finished 6/22/09.
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Joined: Mar 2008
Posts: 3,082
Patient Advocate (old timer, 2000 posts)
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Patient Advocate (old timer, 2000 posts)

Joined: Mar 2008
Posts: 3,082
No noticeable side effects is just the answer I wanted to hear Sandy. Maybe platinum will agree with me better than engineered mouse genes wink
Charm


65 yr Old Frack
Stage IV BOT T3N2M0 HPV 16+
2007:72GY IMRT(40) 8 ERBITUX No PEG
2008:CANCER BACK Salvage Surgery
25GY-CyberKnife(5) 3 Carboplatin
Apaghia /G button
2012: CANCER BACK -left tonsilar fossa
40GY-CyberKnife(5) 3 Carboplatin

Passed away 4-29-13
Joined: Sep 2008
Posts: 489
Platinum Member (300+ posts)
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Platinum Member (300+ posts)

Joined: Sep 2008
Posts: 489
Charm I hope that you continue to have no noticeable side effects and great success with the carboplatin. Hopefully it will make you feel better to know that my doctor said that the people that had the more sever side effects from the Erbitux also had the greatest success with the treatment. You are in my prayers.

Patty


48
SCC Floor of Mouth 7/06
9/06 Surgery, bilateral neck dissection, 58 nodes clear PT2pN0pMx
35 rad 2006
Recurred 6/08, 1 Carboplatin, 1 Cisplatin
Surgery 9/08 - Total glossectomy, free flap from pectoral muscle, left mandible replaced using fibula
35 IMRT & Erbitux 11/08
4/15/09 recurrence
6/1/09 passed away, rest in peace
Good1 #95858 05-21-2009 06:33 PM
Joined: May 2007
Posts: 666
"Above & Beyond" Member (500+ posts)
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"Above & Beyond" Member (500+ posts)

Joined: May 2007
Posts: 666
Charm,
I had carboplatin as well (see my signature for the dosage). Compared to cisplatin it was a non event. Specifically no nausea!! Of course it was getting fairly miserable by week 6 (eating/drinking) but most of that was due to the radiation and not enough nutrition (despite a PEG).
.... BTW I also had no luck with Erbitux...

M



Partial glossectomy (25%) anterior tongue. 4/6/07/. IMRT start @5/24/07 (3x) Erbitux start/end@ 5/24/07. IMRT wider field (30x) start 6/5/07. Weekly cisplatin (2x30mg/m2), then weekly carbo- (5x180mg/m2). End of Tx 19 July 07.
Joined: Jun 2009
Posts: 17
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Posts: 17
My husband started with Erbitux because of poor kidney performance but he fell into the 8% of people who develop mouth and lip sores. It was so bad he looked like he lost a boxing match, including the red eyes. He was switched to Carboplatin and so far (1 treatment) has had no side effects. Meanwhile his face is healing from the Erbitux. He is receiving daily IVs to help his kidneys flush out the platinum.


Husband 79 metastatic cancer neck lymph nodes, biopsy Moffitt showed base of tongue, tonsil & vallecula. VA in Tampa - Teeth out 6/16, Radiation 5X7 and Erbitux 7/13 Carboplatin 8/4 - Amifostine added 8/6

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