Altho John is in such gloomy shape that it's hard to know what is going on when, I am latching on to this thread for a "ray of hope" for some energy boost for him. He has been Levothyroxine 75 mcg for a couple of years. However, he takes it with his am feeding most of the time. Somehow the info about taking it on an empty stomach got lost . I'd like to know what dosage you all are taking and how often you get a thyroid test run. Thanks, Amy