Andy --

I wouldn't rely on Compazine to alleviate the amiphostine nausea. It did zero, zip, nada for Barry -- he had to use Zofran -- and he was the only person in recent times at Hopkins to make it all the way through with the amiphostine -- most give up about 1/2 way through due to nausea. The cisplatin is more of a nausea problem (for many, but not all) than the carboplatin Barry had, as well. You must ask your doc about getting a scrip for one of the serotonin drugs like Zofran, Anzemet, or Kyril or you may not be be a happy camper! (Well, no one is a happy camper during chemoradiation but you get my point...)
This drug should be taken 90 minutes before the amiphostine (per Medimmune's administration directions), along with 20-32 oz. of clear liquid drunk in the 90 minutes leading up to the injection.) And definitely, sub cu injection, not IV!

Ativan may also make you very "out of it" -- Barry tried 1/2 tablet and that still made him too sleepy to drive -- test it at home.

Gail


CG to husband Barry, dx. 7/21/05, age 66, SCC rgt. tonsil, BOT, 2 nodes (stg. IV), HPV+, tonsillectomy, 7x carboplatin, 35x tomoTherapy IMRT w/ Ethyol @ Johns Hopkins, thru treatment 9/28/05, HPV vaccine trial 12/06-present. Looking good!