 "Above & Beyond" Member (500+ posts)
Joined: Jul 2005 Posts: 624 | Andy --
What our radiation nurse recommended was to do teh amiphoistine with teh Zofran the first few times, and try it with Compazine. If you have no problem with it with Zofran, that is. Barry did OK with the Zofran, so tried amiphostine with Compazine, got quite nauseous in afternoon (he received the drug and radiation in late morning) and that was enough to switch him back to the Zofran -- expensive but as he said many times, "worth every penny!"
However two people got really sick (even with Zofran) the first time they took amiphostine so said, "no thanks!" Our RO (who is considered an expert on this drug) said it adds about 10-12% increased salivary sparing to IMRT so it is not the end of the world if you can't take it. That being said, Barry has excellent saliva 5 weeks' out so it undoubtedly helped him.
Gail
CG to husband Barry, dx. 7/21/05, age 66, SCC rgt. tonsil, BOT, 2 nodes (stg. IV), HPV+, tonsillectomy, 7x carboplatin, 35x tomoTherapy IMRT w/ Ethyol @ Johns Hopkins, thru treatment 9/28/05, HPV vaccine trial 12/06-present. Looking good!
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