Andy,
Like other posters, I managed to drive for treatment in the first 2 weeks and I started taking painkillers at the same time even though the pain was very slight in the beginning. My dosage was heavier than Gary's with 4 rounds of cisplatin and 48 sessions of radiation (conventional one). Fatigue was serious when I stepped into the third week and I had to take a taxi to the hospital. I could still go there alone because I didn't want my husband to stay away from his job and all my relatives lived rather far away from me. But about 6 weeks after treatment started, the condition became so bad that I was admitted to hospital for treatment. It was a scary time but I managed to overcome it soon. Take care,
Karen