I think it's way more than 5% that have some sort of difficulty with Amifostine but it probably depends on where you set the bar for difficulty. Just be sure they keep checking your blood pressure. Good luck with the mouthpiece thing...Nelie

SCC(T2N0M0) part.glossectomy & neck dissect 2/9/05 & 2/25/05.33 IMRT(66 Gy),2 Cisplatin ended 06/03/05.Stage I breast cancer treated 2/05-11/05.Surgery to remove esophageal stricture 07/06, still having dilatations to keep esophagus open.Dysphagia. "When you're going through hell, keep going"