Thank you for all the info. My oncologist told me that only 5% of people had a difficult time with amiphostine, but it sounds like most people do. I'm going to give it a try with Zofran and addition fluids administered. How do you suction while receiving treatment? That would make all the difference I think. And I will definately ask about the suction mouthpiece. What is it? The people on this forum are the best. What a great resource to have others with experience. Love to all of you.