Everyone's personal biology will be different. Some antidepressents will work better in some individuals than in others, ditto the amount of impact it has on dry mouth. I started out after treatment on Paxil, it did not produce much of a difference in my dry mouth, but after 6 weeks on the drug, ( SSRI's do not just start working the day that you take them) I felt little improvement in my mental well being. I switched to Lexapro and after about a month had much better results. I was weaned off of SSRI's about a year out of treatment when I began to get adjusted to my new realities. You do not just stop suddenly when you are taking these drugs. As with many things, it may take trying several different anti-depressants before you find one that has the best results for any particular person