Yes, fracture I believe brings it to stage 3. I had more than half thickness of ORN in the mandible, Ramus/Body, as seen on scans, bringing it to late stage ORN, and after 2 years of conservative treatment much like your husbands, and by surgery time, 3 months after being told I needed surgery for late stage ORN, my jaw was fractured, so would have required a mandiblectomy anyway. I also had reconstruction at the same time with a fibula free flap, which may not require HBOT, and due to being vein depleted in my left neck, same side as ORN, the mamary artery and vein were taken from my chest to connect blood flow to the flaps, which included calf muscle/skin due to severe fibrosis in the left neck, which would have been unable tk close during surgery after all my radiation, over 200Gy, and 5 neck dissections.
There are a number of risks for the surgery, which were about 2% with my surgeon for this type surgery, and for me he said it was 5% risk. I think the biggest risen would be flap failure during the first 24 hours or so, and lessened each day, as well as other risks. Several times a day the doctors and nurses in Step Down checked the flaps with a Doppler to hear the blood flow.
Currently I'm in a rehab nursing home for the past 3 weeks since a week after my 8 hour surgery on 9/9, so it takes time to recover, in addition the persons health status and performance factoring in, and type of help you have at home, which was close to 0 for me, so I was sent here for rehab.
As far as the clinical trial with Stem Cells, it's with Dr Marx at the University Miami. As with prior radiation, it may be more problematic, as more research:studies are needed. I read a few articles on this.
http://www.texomashomepage.com/health/mending-mouths-rebuilding-jaw-bones-with-stem-cellsHope this helps
