Yes, toxicities is another factor. Carboplatin works differently on the DNA, than Cisplatin does, but I don't have any trials or info handy with the three drug regimens with all that info or comparisons side by side. Seems most info are scattered about, not cut & dry with different type cancers, drug regimines, radiation or not, etc. If I come across any, I'll let you know.

Here is some info for Induction Chemo, with concurrent cemoradiation with carboplatin, which you may have seen, but has adverse toxicities side by side with TPF vs PF

http://www.hopkinsmedicine.org/otol...20diagnosis%20induction%20with%20TPF.pdf

Here is another study with Cisplatin vv Carboplatin for nasopharyngeal cancer, that lists sdvese effects in both.

http://www.ncbi.nlm.nih.gov/pubmed/17467265

Cisplatin vs Carboplatin HNC:

http://www.medscape.com/viewarticle/708054_6

Last edited by PaulB; 03-17-2013 07:00 AM. Reason: attachments
10/09 T1N2bM0 Tonsil
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