Don't mean to deter you or anything, just telling what was my experience. I haven't heard of similar, and neither have any of my doctors. My current MO said he never heard of someone having a reaction like I did to induction chemo his whole career. Like mentioned, my case is probably rare, and most do fine.
Also, 10 percent or less of oropharyngeal SCC patients present with distant Metastases at diagnosis, so hopefully that's in your favor.