[quote=PaulB]It's not easy, and one of the hardest treatments they say to do. I was fine until I arrived home on the 6th day, and then went straight to the ER by ambulance. I was 48, exercised my whole life, and didn't think anything could knock me down, not even cancer. I was wrong, and this treatment wasn't for me, and went into septic shock, lost 100 pounds, plus a host of other illnesses, which hospitalized me for 6 month, paralyzed from waist down for 10 requiring to go to a nursing home, and now blind in one eye. Actually, I did not even know what chemo I was getting lol, but I'm still here 3 years later, and who knows what would have happened otherwise, and was not debilited by any surgeiries, except for the neck dissections. In retropsect, I would not do it again, and have not fully recovered yet, and my local oncologists, not my treatment doctor who I never went back too, said it was too much chemo. I know others who went though this with no problems, minus a hospitization or two lol, so everyone is different. Good luck with your decision. It's still good if you have choices. [/quote]WHAT THE HELL! This is so far beyond anything I have read so far as a reaction to TPF induction. Especially for an otherwise healthy person and then within six days of starting TPF you go down this horrible path makes me really have to rethink blindly going "all in" on adding TPF to the sequence ahead of standard chemo-radio treatment.

Have you come across any other instance where someone had a reaction that in any way comes close to your experience? I have read about others who had to cut back on dosage or even quit the TPF regime and the typical nausea/vomit stuff. I did read about someone who lost 50% hearing and I do not know if that was permanent or temporary.

God bless you are alive my friend.

Don