It's not easy, and one of the hardest treatments they say to do. I was fine until I arrived home on the 6th day, and then went straight to the ER by ambulance. I was 48, exercised my whole life, and didn't think anything could knock me down, not even cancer. I was wrong, and this treatment wasn't for me, and went into septic shock, lost 100 pounds, plus a host of other illnesses, which hospitalized me for 6 month, paralyzed from waist down for 10 requiring to go to a nursing home, and now blind in one eye. Actually, I did not even know what chemo I was getting lol, but I'm still here 3 years later, and who knows what would have happened otherwise, and was not debilited by any surgeiries, except for the neck dissections. In retropsect, I would not do it again, and have not fully recovered yet, and my local oncologists, not my treatment doctor who I never went back too, said it was too much chemo. I know others who went though this with no problems, minus a hospitization or two lol, so everyone is different. Good luck with your decision. It's still good if you have choices.