Stacy, if you look at the NCCN Guidelines available on this site (see link below) and look up the Occult Primary pages, you will see that radiation or chemo/radiation to the most likely primary site is recommended.
http://oralcancerfoundation.org/treatment/pdf/head-and-neck.pdfPrinting these guidelines had discussing them make a good starting point for discussion.
Best wishes,
Maria