Welcome to OCF! The 3 large doses of cisplatin seem to cause more nausea while the smaller weekly doses are easier to tolerate. I do not know of any research proving the better effectiveness of either method. Chemo is used to help boost the radiation, alone it will not cure the cancer. If I was offered a choice and know now what i didnt then, I would have chosen the smaller weekly doses.

If he will be getting cisplatin, make sure to have a baseline hearing test done as well as a full blood count including thyroid. You may need these results later to use as a reference of where his numbers should be. Many who have had cisplatin report high frequency hearing loss which is permanent (not me).