Please note that studies show that specifically, radiation-enhancing chemotherapy is what has been show to be effective. Given at the same time as the radiotherapy it makes the cancer cells more susceptible to the effects of the radiation. Chemotherapy as most people think of it, as a disease killer used on it's own, when it comes to oral cancers is used in late stage disease where distant mets also need treatment or for palliative care. It is seldom considered as a first line therapeutic for the treatment of oral cancers on its own.