Roma,
You might find it helpful to read the discussion about these chemo option in Wikipedia:
http://en.wikipedia.org/wiki/Panitumumabhttp://en.wikipedia.org/wiki/Cetuximabhttp://en.wikipedia.org/wiki/Cisplatinhttp://en.wikipedia.org/wiki/CarboplatinPanitumumab (Vectibix) is similar to Cetuximab (
Erbitux), monoclonal antibody anti-EGFR drugs. As Charm mentioned, these are not effective against tumors with certain mutations.
Cisplatin and Carboplatin (Platinum based)are similar and seem to also sensitize the cancer cells to radiation. Cisplatin is generally considered a bit more effective, but with more side-effects (liver toxicity and hearing damage).
Many patients have received a combination of both EGFR and Platinum chemo therapy. You might want to asked about a combo regiment.