Bonnie - My prayers will certainly be with you and John and hoping for some of the possible positive outcomes such as Charm's comment about the the chemo and rad working on the tumor since the cells are not really lung cancer cells, but metastic oral cancer cells. It makes sense to me that since the treatment worked on the oral cancer cells, they should work again in their new location. Also, even though you are already at an excellent Cancer facility, I can't help but feel that maybe a 2nd opinion may just have something to add that could help in some way even if it's just to know that they agree with the first opinion. I have heard of lots of people having their tumors shrink or disappear with chemo treatment so "beating the odds" is not out of the question here. I know it must be so devastating to hear a diagnosis with a time limit on life. My older 1/2 sister had breast cancer and was told when she was only 29 with three small children that she had 3 months to live but she went on to live until she was 87! So, anyway, my prayers will be concentrating on all the good stuff that could very well happen. And hopefully the new clinical trial will be another plus in John's recovery.