I don't have a lot of medical info, but I can speak from personal experience. Having a "port" is no big deal. I heardly know it's there. I am doing induction therapy which consists of 3 treatment of Cisplatin, Textara, and 5-fu. I've been told that Cisplatin is very hard on your veins and that is the reason for the port. So whether you do 7day or 3 weeks you may want ask about that aspect of it.