The three treatment plan with Cisplatin was pretty much the gold standard for many years. I read a report that 2 would work as well. Lately they have been doing smaller and more frequent doses, more than likely due to the nephrotoxicity (kidney damage) aspect. It is also easier to manage the nausea with smaller doses. Cisplatin is some nasty stuff. Be SURE to stay hydrated to protect your kidneys. The drug is also more efficacious when you are properly hydrated.