Just to add to the information. My brother was a smokeless tobacco user from the age of 2 years old (yes, 2 years old - my parents thought it was cute because he looked so much like our dad). He started drinking around 16 and I don't think he ever stopped. Probably 6-12 beers a day. Of course, my father blames it all on Agent Orange, which he himself was exposed to in Nam, but that's another story. My brother was not tested for HPV, but I've often wondered. Actually, he was a text book case. Everything they say can cause oral cancer, he did. Drinking, tobacco, hadn't been to the dentist in 12 years. He was a time bomb waiting to go off. I personally think genetics were involved as well since there are many others out there that do all the things he did and live to a ripe old age. I do strongly feel the HPV is something that needs to be looked into. I lost a cousin to cervical cancer about six months before my brother died. She was 41. It was right before all the information about HPV hit the press. She was otherwise healthy with no vises. Go figure.