I also had Erbitux which technically is not chemotherapy but monoclonal antibody therapy. It blocks the EGFR (growth) receptors throughout the body but since the Cancer cells are the hungriest and fastest growing, it hammers them the most. As noted in other posts, there is some evidence that Erbitux also greatly enhances the effect of radiation upon the cancer cells since usually the cancer cells can rebuild themselves faster than normal cells. It is also used when chemo doesn't work out so well. I am convinced it saved me. Less poison and more burning. Although it did take six months for my fingernails to start growing again.