Save yourself a lot of stress and make sure the pills are crushed up really well. I had nexxium that I put through the tube and it wouldn't crush up very well, or dissolve (it's time release but the only way I could take it was through my tube - there was no way I would have been able to swallow a pill) and it would clog up that stupid tube almost every time. We kept some coke on hand for that reason. I spent many mornings in the passenger seat of the car on my way to treatment trying to unclog pills from my tube only to get it unclogged right as we were pulling into the parking lot! Just make sure you crush everything really well and let it dissolve in the water to save your sanity!