In most normal people, acetaldehyde continues to be broken down by the body, into acetic acid and water, eventually. (I think I am remembering my chemistry properly). However, in some people, acetaldehyde is not broken down any further. I believe this is part of the point of the article. For example, in many with the genetic predisposition to alcoholism, acetaldehyde does not get broken down as in a normal person. Instead, it mimimcs the role of brain neurotransmitters. The body then slows, and ultimately ceases, production of the natural neurotransmitter as surplus. Hence the phenomenon of craving that actual alcoholics experience.


A fascinating article, but just the beginning. They need to now see how the substance operates.