We all respond differently to treatment and the meds you are taking factor in as well. My experience here is that the vast majority of people needed drivers, especially from 2-3 weeks into treatment on out. My wife drove me the 60 miles each day to treatment but I also had back-up drivers on tap. ACS reimburses for some of the mileage (I beleive it has a $200 cap - you do have to be at least 60mi from the treatment center, round trip)) as well as providing drivers.