Actually my 45 year old friend did not have ulcers or other digestive issues. He was a perfectly healthy person but had back pain, hence the Naproxen. I took Naproxen myself (also for back pain) but had such severe acid reflux as a result of it I couldn't continue to use it. My understanding is that they now have some analgesics that are coated so that they don't desolve until entering the colon. Maybe some of the COX2 family is in there. Also OTC medications are typically much weaker than their prescriptive counterparts, but I couldn't take Alleve either.

My PDR says that if you take Naprosyn "you should have frequent checkups with your doctor" and "Ulcers and internal bleeding can occur without warning." This is not listed in the "less common or rare side effects" but in the "most important fact about this drug". It can also cause liver disease and "is to be used with caution for people with kidney disease" which are both common issues with many types of chemotherapy (particularly Cisplatin).

I don't make this stuff up - it's right out of the PDR.

Of course having Hep C I am very sensitive about any meds that affect the liver.

Reactionary - you decide.