Heidi, it sounds like he is going to be one of the unlucky in terms of getting walloped by side effects. This will be tough for you both to get through but the PEG will help alot.My suggestion to you is that you ask him continually to tell you if he is in pain and, if so, you insist on adequate medication for him. In our case, the radiation was much harder than the chemo [Carboplatin\Taxol and now Erbitux] I feel for you- this is a really hard thing to watch your husband go through. You are going to have to be very strong. Keep posting and e-mail any of us that you think might help you cope. Amy